Cardiac extracellular volume quantified with T1 mapping techniques reflects degree of cardiac and neurological involvement in Hereditary Transthyretin Amyloidosis
نویسندگان
چکیده
Background Amyloidotic cardiomyopathy (AC) in Hereditary Transthyretin Amyloidosis (ATTR) determines prognosis and treatment options. Cardiac Magnetic Resonance (CMR) has shown its utility in the diagnosis and characterization of AC. Moreover, CMR T1 mapping techniques are useful to assess myocardial extracellular volume (ECV) fraction in AC. We hypothesized that ECV allows identification of AC in ATTR patients and that there is a correlation between cardiac ECV and the degree of neurological impairment caused by TTR amyloid extracardiac deposits.
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عنوان ژورنال:
دوره 10 شماره
صفحات -
تاریخ انتشار 2015